Wang, Z., Choi, M.K., Ban, T., Yanai, H., Negishi, H., Lu, Y., Tamura, T., Takaoka, A., Nishikura, K., and Taniguchi, T.Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.Proc. Natl. Acad. Sci. USA, 105, 5477-5482, 2008.
Takaoka, A., and Taniguchi, T.Cytosolic DNA recognition for triggering innate immune responses.Advanced Drug Delivery Reviews, 60, 847-857, 2008.
Takaoka, A., Tamura, T., and Taniguchi, T.IRF family of transcription factors and regulation of oncogenesis.Cancer Sci., 99, 467-478, 2008.
Takaoka, A., Wang, Z., Choi, M.K., Yanai, H., Negishi, H., Ban, T., Lu, Y., Miyagishi, M., Kodama, T., Honda, K., Ohba, Y., and Taniguchi, T.DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.Nature , 448, 501-505, 2007.
Yanai, H., Chen, H., Inuzuka, T., Kondo, S., Mak, W. T., Takaoka. A., Honda, K. and Taniguchi, T.Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.Proc. Natl. Acad. Sci. USA, 104, 3402-3407, 2007.
Imai, K., and Takaoka, A.Comparing antibody and small-molecule therapies for cancer.Nat. Rev. Cancer, 6, 714-727, 2006.
Takaoka, A., and Yanai, H.Interferon signalling network in innate defence.Cell. Microbiol., 8, 907-922, 2006.
Shibue, T., Suzuki, S., Okamoto, H., Yoshida, H., Ohba, Y., Takaoka, A., and Taniguchi, T.Differential contribution of Puma and Noxa in dual regulation of p53-dependent apoptotic pathways.EMBO. J., 25, 4952-4962, 2006.
Honda, K., Takaoka, A., and Taniguchi, T.Type I interferon gene induction by the interferon regulatory factor family of transcription factors.Immunity, , 25(3):349-60, 2006.
Yanai H., Mizutani T., Inuzuka T., Honda K., Takaoka A. and Taniguchi T.IRF family transcription factors in type I interferon induction.Int. Congress Series, 1285, 104-113, 2005.
Honda K., Yanai H., Takaoka A., and Taniguchi T.Regulation of the type I IFN induction: a current view.Int. Immunol., 17, 1367-1378, 2005.
Negishi H., Ohba Y., Yanai H., Takaoka A., Honma K., Yui K., Matsuyama T., Taniguchi T., and Honda K.Negative regulation of Toll-like-receptor signaling by IRF-4.Proc. Natl. Acad. Sci. USA., 102, 15989-15994, 2005.
Takayanagi H., Sato K., Takaoka A., and Taniguchi T.Interplay between interferon and other cytokine systems in bone metabolism.Immunol. Rev., 208, 181-193, 2005.
Honda K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., and Taniguchi, T.Spatiotemporal regulation of MmyD88-IRF-7 signalling for robust type I interferon induction.Nature, 434, 1035-1040, 2005.
Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., and Taniguchi T.IRF-7 is the master regulator of type-I interferon-dependent immune responses.Nature, 434, 772–777, 2005.
Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., and Taniguchi T.Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.Nature, 434, 243-249, 2005.
Taniguchi, T., and Takaoka, A.Type I interferon system and IRF family of transcription factors in host defense regulation.Proc. Jpn. Acad., 81, 1-13, 2005.
Honda, K., Yanai, H., Mizutani, T., Negishi, H., Shimada, N., Suzuki, N., Ohba, Y., Takaoka, A., Wen-Chen Yeh, and Taniguchi, T.Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.Proc. Natl. Acad. Sci. USA, 101, 15416-15421, 2004.
Takaoka, A. and Taniguchi, T.New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism.Gann Monograph on Cancer Research, 52, 141-156, 2004.
Honda, K., Sakaguchi, S., Nakajima, C., Watanabe, A., Yanai, H., Matsumoto, M., Ohteki, T., Kaisho, T., Takaoka, A., Akira, S., Seya, T., and Taniguchi, T.Selective contribution of IFN-a/b signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection.Proc. Natl. Acad. Sci. USA , 100, 10872-10877, 2003.
Shibue, T., Takeda, K., Oda, E., Tanaka, H., Murasawa, H., Takaoka, A., Morishita, Y., Akira, S., Taniguchi, T., and Nobuyuki Tanaka, N.Integral role of Noxa in p53-mediated apoptotic response.Genes. Dev., 17, 2233-2238, 2003.
Takaoka, A., Hayakawa, K., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Shibue, T., Honda, K., and Taniguchi, T.Integration of IFN-a/b signalling to p53 responses in tumor suppression and antiviral defense.Nature, 424, 516-523, 2003.
Sakaguchi, S., Negishi, H., Asagiri, M., Nakajima, C., Mizutani, T., Takaoka, A., Honda, K., and Taniguchi, T.Essential role of IRF-3 in lipopolysaccharide-induced interferon-β gene expression and endotoxin shock.Biochem Biophys Res Commun, 306, 806-866, 2003.
Takaoka, A., and Taniguchi, T.New aspects of IFN-α/βsignaling in immunity, oncogenesis and bone metabolism.Cancer Science, 94, 405-411, 2003.
Taniguchi, T., Takaoka, A.Interferon-α/β system in antiviral response: Multimodal machinery of gene regulation by the IRF family of transcription factors.Curr. Opin. Immunol., 14, 111-116, 2002.
Mitani, Y., Takaoka, A., Kim, S. H., Kato, Y., Yokochi, T., Tanaka, N., and Taniguchi, T.Cross talk of the interferon-α/β signaling complex with gp130 for effective interleukin-6 signaling.Genes to Cells, 6, 631-640, 2001.
Hata, N. Sato, M. Takaoka, A. Asagiri, M. Tanaka, N. Taniguchi, T.Constitutive IFN-α/β signal for efficient IFN-α/β gene induction by virus.Biochem Biophys Res Commun, 285, 518-525, 2001.
Taniguchi, T. and Takaoka, A.A weak signal for strong responses: Interferon-α/β Revisited.Nature Rev. Mol. Cell Biology, 2, 378-386, 2001.
Taniguchi, T., Ogasawara, K., Takaoka, A, and Tanaka, N.IRF family of transcription factors as regulators of host defense.Ann. Rev. Immunol., 19, 623-655, 2001.
Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, k. and Taniguchi, T.T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ.Nature, 408, 600-605, 2000.
Tsujino, S., Di Santo, J. P.,Takaoka, A., Mckernan,T. L., Noguchi, S., Taya, C., Yonekawa, H., Saito, T., Taniguchi, T., and Fujii, H.Differential requirement of the cytoplasmic subregions of γ c chain in T cell development and function.Proc. Natl. Acad. Sci. USA, 97, 10514-10519, 2000.
Takaoka, A., Mitani, Y., Suemori, H., Sato, S., Yokochi, T., Noguchi, S., Tanaka, N., and Taniguchi, T.Crosstalk between interferon-γ and-α/β signaling components at caveolar membrane domain.Science, 288, 2357-2360, 2000.
Taniguchi, T., Tanaka, N., Ogasawara, K., Taki, S., Sato, M. and Takaoka, A.The transcription factor IRF-1 and its family members in the regulation of host defense.Cold Spring Harbor Symposia on Quantitative Biology, 64, 465-472, 1999.
Taniguchi, T., Tanaka, N., Ogasawara, K., Hida, S., Sato, M. and Takaoka, A.Regulation of interferon and immune systems by the IRF family of transcription factors.J. Interferon and Cytokine Res., 19(Sup. 1), S55, 1999.
Takaoka, A., Tanaka, N., Mitani, Y., Miyazaki, T., Fujii, H., Sato, M., Kovarik, P,. Decker, T., Schlessinger, J. and Taniguchi, T.Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in the IFN-γ, but not IFN-α, signaling.EMBO. J., 18, 2480-2488, 1999.
Takaoka, A., Hinoda, Y., Sato, S., Adachi, Y., Itoh, F., Adachi, M., and Imai, K.Suppression of invasive properties of colon cancer cells by a metastasis suppressor KAI1 gene.Oncogene, 16, 1443-1453, 1998.
Takaoka, A., Hinoda, Y., Sato, S., Itoh, F., Adachi, M., and Imai, K. Reduced invasive and metastatic potentials of KAI1-transfected melanoma cells. Jpn. J. Cancer Res., 98, 397-404, 1998.
Hinoda, Y., Adachi, Y., Takaoka, A., Mitsuuchi, H., Satoh, Y., Itoh, F., Kondoh, Y., and Imai, K. Decreased expression of the metastasis suppressor gene KAI1 in gastric cancer. Cancer Lett., 129, 229-234, 1998.
Miyazaki, T., Takaoka, A., Noguerira, L., Dikic, I., Fujii, H., Tsujino, S., Mitani, Y., Maeda, M., Schlessinger, J. and Taniguchi, T.Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak-signaling pathway.Genes. Dev., 12, 770-775, 1998.
Takaoka, A., Toyota, M., Hinoda, Y., Itoh, F., Mita, H., Kakiuchi, H., and Imai, K.Expression and identification of aberrant c-kit transcripts in human cancer cells.Cancer Lett., 115, 257-261, 1997.
Takaoka, A., Adachi, M., Okuda, H., Sato, S., Yawata, A., Hinoda, Y., Takayama, S., Reed, J.C., and Imai, K.Anti-cell death activity promotes pulmonary metastasis of melanoma cells.Oncogene, 14, 2971-2977, 1997.
Toyota, M., Hinoda, Y., Nakagawa, N., Arimura, Y., Tokuchi, S., Takaoka, A., Kitagawa, S., Usuki, T., Yabana, T., Yachi, A., and Imai, K.Gastric antral vascular ectasia causing severe anemia. J. Gastroenterol.J. Gastroenterol., 31, 710-713, 1996.
Toyota, M., Hinoda, Y., Itoh, F., Takaoka, A., Imai, K., and Yachi, A.Complementary DNA cloning and characterization of truncated form of c-kit in human colon carcinoma cells.Cancer Res., 54, 272-275, 1994.
Toyota, M., Hinoda, Y., Takaoka, A., Makiguchi, Y., Takahashi, T., Itoh, F., Imai, K., and Yachi, A.Expression of c-kit and kit ligand in human colon carcinoma cells.Tumour Biol., 14, 295-302, 1993.
Nishi, M., Miyake, H., Ito, Y., Kagiichi, S., Kimura, M., Suzuki, A., Takaoka, A., Tago, N., and Nagase, K.Uptake of immunization of children with asthma.Acta. Paediatr. Jpn., 32, 328-329, 1990.
Nishi, M., Miyake, H., Ito, Y., Kagiichi, S., Kimura, M., Suzuki, A., Takaoka, A., Tago, N. and Nagase, K.Vaccination of children in Japan.Asia. Pac. J. Public Health.l., 4, 128-131, 1990.