北大遺伝子病制御研究所から、以下の3件の研究成果が報告されました。

・Shimoyama S, Nakagawa I, Jiang J-J, Matsumoto I, Chiorini JA, Hasegawa Y, Ohara O, Hasebe R, Ota M, Uchida M, Kamimura D, Hojyo S, Tanaka Y, Atsumi T, Murakami M. Sjögren’s syndrome-associated SNPs increase GTF2I expression in salivary gland cells to enhance inflammation development. Int Immunol. in press

・Uchida M, Yamamoto R, Matsuyama S, Murakami K, Hasebe R, Hojyo S, Tanaka Y, Murakami M. Gateway reflexes, neuronal circuits that regulate the gateways for autoreactive T cells in organs that have blood barriers. Int Immunol. in press dxab022 (2021) doi: 10.1093/intimm/dxab022

・Murakami K, Kamimura D, Hasebe R, Uchida M, Abe N, Yamamoto R, Jiang J-J, Hidaka Y, Nakanishi Y, Fujii S, Toda Y, Toda N, Tanaka H, Akira S, Tanaka Y, Murakami M. Rhodobacter azotoformans BP0899 LPS（RAP99-LPS） is a TLR4 agonist that inhibits lung metastasis and enhances TLR3-mediated chemokine expression. Front Immunol.