2022

Kaori Kanemaru, Makoto Shimozawa, Manabu Kitamata, Rikuto Furuishi, Hinako Kayano, Yui Sukawa, Yuuki Chiba, Takatsugu Fukuyama, Junya Hasegawa, Hiroki Nakanishi Takuma Kishimoto, Kazuya Tsujita, Kazuma Tanaka, Toshiki Itoh, Junko Sasaki, Takehiko Sasaki, Kiyoko Fukami, Yoshikazu Nakamura.
Plasma membrane phosphatidylinositol (4,5)-bisphosphate is critical for determination of epithelial characteristics.
Nat Commun. 2022 May 9;13(1):2347. doi: 10.1038/s41467-022-30061-9.[PubMed]

Tetsuo Mioka, Tian Guo, Shiyao Wang, Takuma Tsuji, Takuma Kishimoto, Toyoshi Fujimoto, Kazuma Tanaka.
Characterization of micron-scale protein-depleted plasma membrane domains in phosphatidylserine-deficient yeast cells.
J Cell Sci. 2022 Mar 1;135(5):jcs256529. doi: 10.1242/jcs.256529.[PubMed]

2021

Takuma Kishimoto, Tetsuo Mioka, Eriko Itoh, David E Williams, Raymond J Andersen, Kazuma Tanaka.
Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane.
Mol Biol Cell. 2021 Jul 15;32(15):1374-1392. doi: 10.1091/mbc.E20-11-0699.[PubMed]

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2020

Mamoru Miyasaka, Tetsuo Mioka, Takuma Kishimoto, Eriko Itoh, Kazuma Tanaka
A complex genetic interaction implicates that phospholipid asymmetry and phosphate homeostasis regulate Golgi functions.
PLoS One . 2020 Jul 30;15(7):e0236520. doi: 10.1371/journal.pone.0236520. eCollection 2020.[PubMed]

Tomomi Suzuki, Tetsuo Mioka, Kazuma Tanaka, Akira Nagatani
An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast.
Sci Rep. 2020 Jul 27;10(1):12474. doi: 10.1038/s41598-020-69459-0.[PubMed]

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2018

Mioka T, Fujimura-Kamada K, Mizugaki N, Kishimoto T, Sano T, Nunome H, Williams DE, Andersen RJ, Tanaka K.
Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane.
Mol Biol Cell. 2018 May 15;29(10):1203-1218. [PubMed]

Suito T, Nagao K, Hatano M, Kohashi K, Tanabe A, Ozaki H, Kawamoto J, Kurihara T, Mioka T, Tanaka K, Hara Y, Umeda M.
Synthesis of omega-3 long-chain polyunsaturated fatty acid-rich triacylglycerols in an endemic goby, Gymnogobius isaza, from Lake Biwa, Japan.
J Biochem. 2018 Aug 1;164(2):127-140. doi: 10.1093/jb/mvy035. [PubMed]

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2017

Yamamoto T, Fujimura-Kamada K, Shioji E, Suzuki R, Tanaka K.
Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast.
G3 (Bethesda). 2017 Jan 5;7(1):179-192. [PubMed]

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2015

Yamagami K, Yamamoto T, Sakai S, Mioka T, Sano T, Igarashi Y, Tanaka K.
Inositol Depletion Restores Vesicle Transport in Yeast Phospholipid Flippase Mutants.
PLoS One. 2015 Mar;10(3):e0120108. [PubMed]

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2014

Mioka T, Fujimura-Kamada K, Tanaka K.
Asymmetric distribution of phosphatidylserine is generated in the absence of phospholipid flippases in Saccharomyces cerevisiae.
Microbiologyopen. 2014 Oct;3(5):803-821. [PubMed]

Takeda M, Yamagami K, Tanaka K.
Role of phosphatidylserine in phospholipid flippase-mediated vesicle transport in yeast.
Eukaryot Cell. 2014 Mar;13(3):363-375. [PubMed]

Hanamatsu H, Fujimura-Kamada K, Yamamoto T, Furuta N,and Tanaka K.
Interaction of the phospholipid flippase Drs2p with the F-box protein Rcy1p plays an important role in early endosome to trans-Golgi network vesicle transport in yeast.
J Biochem. 2014 Jan;155(1):51-62. [PubMed]

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2013

Zendeh-Boodi Z, Yamamoto T, Sakane H, Tanaka K.
Identification of a second amphipathic lipid-packing sensor-like motif that contributes to Gcs1p function in the early endosome-to-TGN pathway.
J Biochem. 2013 Apr 26. [PubMed]

Hachiro T, Yamamoto T, Nakano K, Tanaka K.
Phospholipid flippases Lem3p-Dnf1p and Lem3p-Dnf2p are involved in the sorting of the tryptophan permease Tat2p in yeast.
J Biol Chem. 2013 Feb 1;288(5):3594-3608. [PubMed]

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2012

Aihara Y, Yamamoto T, Okajima K, Yamamoto K, Suzuki T, Tokutomi S, Tanaka K, Nagatani A.
Mutations in the N-terminal flanking region of the blue-light sensing domain LOV2 disrupt its repressive activity on the kinase domain in the Chlamydomonas phototropin.
J Biol Chem. 2012 Mar;287(13):9901-9909. [PubMed]

Fujimura-Kamada K, Hirai T, Tanaka K.
Essential Role of the NH2-Terminal Region of Cdc24 Guanine Nucleotide Exchange Factor in Its Initial Polarized Localization in Saccharomyces cerevisiae.
Eukaryot Cell. 2012 Jan;11(1):2-15. [PubMed]

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2011

Takahashi Y, Fujimura-Kamada K, Kondo S, Tanaka K.
Isolation and characterization of novel mutations in CDC50, the non-catalytic subunit of the Drs2p phospholipid flippase.
J Biochem. 2011 Apr;149(4):423-432. [PubMed]

Tanaka K, Fujimura-Kamada K, Yamamoto T.
Functions of phospholipid flippases.
J Biochem. 2011 Feb;149(2):131-143. [PubMed]

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2010

Yamamoto T, Mochida J, Kadota J, Takeda M, Bi E, Tanaka K.
Initial Polarized Bud Growth by Endocytic Recycling in the Absence of Actin Cable-dependent Vesicle Transport in Yeast.
Mol Biol Cell. 2010 Apr 1;21(7):1237-1252. [PubMed]

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2008

Nakano K, Yamamoto T, Kishimoto T, Noji T, Tanaka K.
Protein Kinases Fpk1p and Fpk2p are Novel Regulators of Phospholipid Asymmetry.
Mol Biol Cell. 2008 Apr;19(4):1783-1797. [PubMed]

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2007

Saito K, Fujimura-Kamada K, Hanamatsu H, Kato U, Umeda M, Kozminski KG, Tanaka K.
Transbilayer Phospholipid Flipping Regulates Cdc42p Signaling during Polarized Cell　Growth via Rga GTPase-Activating Proteins.
Dev Cell. 2007 Nov;13(5):743-751. [PubMed]

Furuta N, Fujimura-Kamada K, Saito K, Yamamoto T, Tanaka K.
Endocytic Recycling in Yeast Is Regulated by Putative Phospholipid Translocases and the　Ypt31p/32p-Rcy1p Pathway.
Mol Biol Cell. 2007 Jan;18(1):295-312. [PubMed]

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2006

Sakane H, Yamamoto T, Tanaka K.
The functional relationship between the Cdc50p-Drs2p putative aminophospholipid translocase and the Arf GAP Gcs1p in vesicle formation in the retrieval pathway from yeast early endosomes to the TGN.
Cell Struct Funct. 2006;31(2):87-108. [PubMed]

Noji T, Yamamoto T, Saito K, Fujimura-Kamada K, Kondo S, Tanaka K.
Mutational analysis of the Lem3p-Dnf1p putative phospholipid-translocating P-type ATPase reveals novel regulatory roles for Lem3p and a carboxyl-terminal region of Dnf1p independent of the phospholipid-translocating activity of Dnf1p in yeast.
Biochem. Biophys. Res. Commun. 2006 May 26;344(1):323-331. [PubMed]

Yoshiuchi S, Yamamoto T, Sakane H, Kadota J, Mochida J, Asaka M, Tanaka K.
Identification of novel mutations in ACT1 and SLA2 that suppress the actin cable-overproducing phenotype caused by overexpression of a dominant active form of Bni1p in Saccharomyces cerevisiae.
Genetics. 2006 Jun;173(2):527-539. [PubMed]

岸本拓磨、山本隆晴、田中一馬
細胞極性形成におけるアクチン細胞骨格再編成の膜脂質による制御
『蛋白質　核酸　酵素』　51巻6: 767頁-775頁

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2005

Kishimoto T, Yamamoto T, Tanaka K.
Defects in Structural Integrity of Ergosterol and the Cdc50-Drs2p Putative Phospholipid Translocase Cause Accumulation of Endocytic Membranes onto Which Actin Patches Are Assembled in Yeast.
Mol Biol Cell. 2005 Dec;16(12):5592-5609. [PubMed]

斉藤康二、鎌田(藤村)このみ、田中一馬
生体膜脂質の非対称性が細胞機能の制御に果たす役割
『蛋白質　核酸　酵素』　50巻2: 148頁-154頁

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2004

Kadota J, Yamamoto T, Yoshiuchi S, Bi E, Tanaka K.
Septin Ring Assembly Requires Concerted Action of Polarisome Components,a PAK Kinase Cla4p, and the Actin Cytoskeleton in Saccharomyces cerevisiae.
Mol Biol Cell. 2004 Dec;15(12):5329-5345. [PubMed]

Saito K, Fujimura-Kamada K, Furuta N, Kato U, Umeda M, Tanaka K.
Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase, implicated in phospholipid translocation in Saccharomyces cerevisiae.
Mol Biol Cell. 2004 Jul;15(7):3418-3432. [PubMed]

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2003

Toi H, Fujimura-Kamada K, Irie K, Takai Y, Todo S, and Tanaka K.
She4p/Dim1p interacts with the motor domain of unconventional myosins in the budding yeast, Saccharomyces cerevisiae.
Mol Biol Cell. 2003 Jun;14(6):2237-2249. [PubMed]

Kawasaki R, Fujimura-Kamada K, Toi H, Kato H, and Tanaka K.
The upstream regulator, Rsr1p, and downstream effectors, Gic1p and Gic2p, of the Cdc42p small GTPase coordinately regulate initiation of budding in Saccharomyces cerevisiae.
Genes Cells. 2003 Mar;8(3):235-250. [PubMed]

Misu K, Fujimura-Kamada K, Ueda T, Nakano A, Katoh H, and Tanaka K.
Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae.
Mol Biol Cell. 2003 Feb;14(2):730-747. [PubMed]

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2002

Mochida J, Yamamoto T, Fujimura-Kamada K, and Tanaka K.
The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.
Genetics. 2002 Mar;160(3):923-934. [PubMed]

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2001

Tanaka K, and Matsui Y.
Functions of unconventional myosins in the yeast Saccharomyces cerevisiae.
Cell Struct. Funct. 2001 Dec;26(6):671-675. [PubMed]

Saka A, Abe M, Okano H, Qadota H, Utsugi T, Mino A, Tanaka K, Takai Y, and Ohya Y.
Complementing yeast rho1 mutation groups with distinct functional defects.
J. Biol. Chem. 2001 Dec 7;276(49):46165-46171. [PubMed]

Inoue H, Tateno M, Fujimura-Kamada K, Takaesu G, Adachi-Yamada T, Ninomiya-Tsuji J, Irie K, Nishida Y, Matsumoto K.
A Drosophila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK.
EMBO J. 2001 Oct 1;20(19):5421-5430. [PubMed]

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2000

Tanaka, K.
Formin family proteins in cytoskeletal control.
Biochem. Biophys. Res. Commun. 2000 Jan 19;267(2):479-481. [PubMed]

田中一馬
出芽酵母における細胞極性形成の分子機構
『生体の科学』　51巻2号: 91頁-95頁

田中一馬
Two hybrid法を始めたばかりの人のために
『細胞工学』　19巻3号: 477頁-480頁

田中一馬
神経伝達物質の放出におけるSNARE系の作用機構
『脳の科学』　22巻: 801頁-804頁

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